Capsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It induces inward currents in HEK293 cells expressing rat transient receptor potential vanilloid 1 (TRPV1, EC50 = 0.64 µM at neutral pH), an effect that can be blocked by the TRPV1 inhibitor A-425619. Capsaicin (10...

Description: Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 µM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities. Target: Autophagy, TRP/TRPV Channel, Apoptosis. Smiles:...

Capsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It induces inward currents in HEK293 cells expressing rat transient receptor potential vanilloid 1 (TRPV1, EC50 = 0.64 µM at neutral pH), an effect that can be blocked by the TRPV1 inhibitor A-425619. Capsaicin (10...

(Capsaicin, ?65%, dihydrocapsaicin, ~20%, nordihydrocapsaicin, ~4 %) Capsaicin is a powerful irritant isolated from Capsicum or Solanaceae. It has been used in the clinical treatment postherpetic neuralgia.

Primary active component of the heat and pain-eliciting lipid-soluble fraction of Capsicum pepper. Acts as an agonist at the vanilloid receptor (VR1, TRPV1) receptor, a ligand-gated non-selective cation channel. Capsaicin elicits a sensation of burning pain by activation of TRPV1 on small, non-myelinated polymodal...