Description: HEMADO is a potent and selective agonist of the adenosine A3 receptor [Ki: 1.1 nM at the human A3 subtype]. Target: Others. Smiles: O[C@H]1[C@H](N2C=3C(N=C2)=C(NC)N=C(C#CCCCC)N3)O[C@H](CO)[C@H]1O. References: Klotz KN, et al. [3H]HEMADO- a novel tritiated agonist selective for the human adenosine A3...

HEMADO is a selective agonist of the adenosine A3 receptor (Kis = 1.1, 327, and 1,230 nM for A3, A1, and A2A receptors, respectively). HEMADO reduces release of lactate dehydrogenase (LDH) and creatine kinase-MB (CK-MB) from myocardium in isolated rat hearts subjected to ischemia-reperfusion injury.Formal Name:...