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Item number: Cay42893-10

Firategrast is an antagonist of integrin alpha4beta1, also known as very late antigen-4 (VLA-4), and integrin alpha4beta7. Maternal administration of firategrast (100 mg/kg) increases the number of donor hematopoietic stem cells (HSCs) in fetal liver in a mouse model of in utero allogeneic HSC transplant.....

Keywords:	SB-683699, aS-[(2,6-difluorobenzoyl)amino]-4'-(ethoxymethyl)-2',6'-dimethoxy-[1,1'-biphenyl]-4-propanoic acid
Application:	Integrin alpha4beta1 / integrin alpha4beta7 antagonist
CAS	402567-16-2
MW:	499.51 D

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Firategrast

Item number: TGM-TQ0291-100mg

Description: Firategrast (SB 683699) is an orally active and specific alpha4beta1/alpha4beta7 integrin antagonist that reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity. It is used in relapsing-remitting multiple sclerosis, associated with...

Keywords:	SB 683699
Application:	Targets integrin alpha 4 (ITGA4, CD49d)
CAS	402567-16-2
MW:	499.5 D

From 38.00€ *

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