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JNJ-5207852
JNJ-5207852

Item number: Cay11998-10

Histamine has been implicated in a variety of biological functions including thermo- and immunoregulation, food intake, hyperexcitability, pain transmission, arousal, reward, memory, and emotional responses. The histamine H3 receptor is a Gi-coupled presynaptic auto- and hetero-receptor whose activation leads to a...
Keywords: 1-[3-[4-(1-piperidinylmethyl)phenoxy]propyl]-piperidine
Application: Histamine H3R antagonist
CAS 398473-34-2
MW: 316.5 D
From 133.00€ *
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JNJ-5207852
JNJ-5207852

Item number: TGM-T7413-100mg

Description: JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. Target: Histamine Receptor. Smiles: C(COC1=CC=C(CN2CCCCC2)C=C1)CN1CCCCC1. References: Esbenshade T A , Browman K E , Bitner R S , et al. The histamine H3...
Application: Histamine H3R antagonist
CAS 398473-34-2
MW: 316.48 D
From 30.00€ *
Review