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Item number: TGM-T35643-1mg

Description: 4-hydroperoxy Cyclophosphamide (4-OOH-CY) is the active metabolite form of the prodrug Cyclophosphamide. 4-OOH-CY crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS).[1]...

Keywords:	4-hydroperoxy Cyclophosphamide, 4-OOH-CY
CAS	39800-16-3
MW:	293.08 D

229.00€ *

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4-hydroperoxy Cyclophosphamide

Item number: Cay19527-1

4-hydroperoxy cyclophosphamide (4-OOH-CY) is an activated analog of cyclophosphamide (Cay-13849). 4-OOH-CY (1 and 3 µg/ml) crosslinks DNA and induces T cell apoptosis independent of death receptor activation but activates mitochondrial death pathways through the production of reactive oxygen species (ROS). In vivo,...

Keywords:	4-OOH-CY, 2-[bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl, hydroperoxide
Application:	Cyclophosphamide metabolite
CAS	39800-16-3
MW:	293.1 D

From 126.00€ *

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