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16,16-dimethyl Prostaglandin E2
16,16-dimethyl Prostaglandin E2

Item number: Cay14750-1

16,16-dimethyl PGE2 is a competitive inhibitor of 15-hydroxy PGDH, but it is not a substrate for the enzyme. Because of its resistance to metabolism by 15-hydroxy PGDH, it has a prolonged half-life in vivo. 16,16-dimethyl PGE2 acts as an agonist on most EP receptor subtypes, and has been used experimentally to...
Keywords: 16,16-dimethyl PGE2, 9-oxo-11alpha,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid
Application: PGDH inhibitor
CAS 39746-25-3
MW: 380.5 D
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