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Item number: Cay16615-10

BVT 948 is a noncompetitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTP, IC50s = 0.09-1.7 µM). It facilitates the oxidation of the catalytic cysteine residue by hydrogen peroxide. Similarly, it inhibits redox-sensitive cytochrome P450 (CYP) isoforms, including CYP2C19 and CYP2D6, with IC50 values...

Keywords:	4-hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione
Application:	Noncompetitive, cell-permeable protein tyrosine phosphatase inhibitor
CAS	39674-97-0
MW:	241.2 D

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BVT948

Item number: TGM-T14841-5mg

Description: BVT948 is a protein tyrosine phosphatase (PTP) inhibitor that also inhibits lysine methyltransferase SETD8 (KMT5A) and various cytochrome P450 (P450) isoforms. Target: Phosphatase, Histone Methyltransferase, P450. Smiles: CC1(C)C(=O)N=C2C1=C(O)C(=O)c1ccccc21. References: Liljebris C, et al. Oxidation...

CAS	39674-97-0
MW:	241.24 D

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