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Tiplaxtinin
Item number: Cay9000450-1
Tiplaxtinin is an inhibitor of plasminogen activator inhibitor 1 (PAI-1, IC50 = 2.7 µM for the human enzyme). It inhibits differentiation of human adipocytes when used at a concentration of 5 µM. Tiplaxtinin (5 and 20 mg/kg) reduces tumor growth and microvessel density in a T24 bladder cancer mouse xenograft model....
| Keywords: | PAI-039, Tiplasinin, alpha-oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid |
| Application: | PAI-1 inhibitor |
| CAS | 393105-53-8 |
| MW: | 439.4 D |
From 67.00€
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Tiplaxtinin
Item number: LKT-T3461.1
PAI-1 inhibitor.
| Keywords: | PAI-039 |
| Application: | Treatment of fibrinolytic impairment diseases |
| CAS | 393105-53-8 |
| MW: | 439.39 D |
From 94.00€
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Tiplaxtinin
Item number: TGM-T2030-100mg
Description: Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM. Target: Apoptosis, PAI-1. Smiles: OC(=O)C(=O)c1cn(Cc2ccccc2)c2ccc(cc12)-c1ccc(OC(F)(F)F)cc1. References: Elokdah H, et al. J Med Chem. 2004, 47(14),...
| Keywords: | Tiplasinin, PAI-039 |
| CAS | 393105-53-8 |
| MW: | 439.38 D |
From 36.00€
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