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UC-112
UC-112

Item number: Cay45378-10

UC-112 is a Smac mimetic. It reduces the level of survivin and induces apoptosis in A375 melanoma and PC3 prostate cancer cells and inhibits the growth of A375, M14 human melanoma, PC3 and DU145 prostate cancer cells (IC50s = 1.6, 2.5, 0.7, and 3.4 µM, respectively). In vivo, UC-112 (20 and 40 mg/kg) reduces tumor...
Keywords: 5-[(phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol
Application: Smac mimetic
CAS 383392-66-3
MW: 348.45 D
From 189.00€ *
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UC-112
UC-112

Item number: TGM-T17195-100mg

Description: UC-112 is a novel, potent IAP inhibitor that effectively inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM). Target: Others. Smiles: Oc1c(CN2CCCC2)cc(COCc2ccccc2)c2cccnc12. References: Wang J, et al. Discovery of novel second mitochondria-derived...
CAS 383392-66-3
MW: 348.44 D
From 30.00€ *
Review