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Item number: TGM-T22748-10mg

Description: DQP 1105 is a NMDA receptor antagonist. Target: NMDAR. Smiles: Cc1ccc2[nH]c(=O)c(C3=NN(C(C3)c3ccc(Br)cc3)C(=O)CCC(O)=O)c(-c3ccccc3)c2c1. References: Lozovaya N, Gataullina S, et al. Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model. Nat...

CAS	380560-89-4
MW:	558.42 D

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DQP1105

Item number: Cay31121-1

DQP1105 is an NMDA receptor antagonist. It selectively inhibits glutamate-induced currents in Xenopus oocytes expressing rat NR2C and NR2D subunit-containing NMDA receptors (IC50s = 8.5 and 2.7 µM, respectively) over NR2A, NR2B, NRA1, and NRK2 subunit-containing receptors (IC50s = 206, 121, 198, and 153 µM,...

Keywords:	5-(4-bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-gamma-oxo-1H-pyrazole-1-butanoic acid
Application:	NMDA receptor antagonist
CAS	380560-89-4
MW:	558.4 D

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