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Item number: Cay11497-5

Saracatinib is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). It less effectively inhibits other receptor and non-receptor tyrosine kinases as well as assorted serine/threonine kinases. Saracatinib is orally available and blocks cell motility, migration, adhesion,...

Keywords:	AZD 0530,...
Application:	c-Src / Abl inhibitor
CAS	379231-04-6
MW:	542 D

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Saracatinib, Free Base...

Item number: S0097-50.10

Saracatinib an orally available Src kinase inhibitor. Saracatinib inhibits c-Src and Abl enzymes at low nanomolar concentrations. Saracatinib blocked the tumor growth of a c-Src-transfected 3T3-fibroblast xenograft in vivo and increased significantly the survival of animals in a highly aggressive model of human...

CAS	379231-04-6
MW:	542.03

241.00€ *

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Saracatinib

Item number: TGM-T6078-100mg

Description: Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes. Target: BTK, Src, EGFR, Autophagy. Smiles: CN1CCN(CCOc2cc(OC3CCOCC3)c3c(Nc4c5OCOc5ccc4Cl)ncnc3c2)CC1. References: Green TP, et al. Preclinical anticancer activity of the...

Keywords:	AZD0530
Application:	Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1)
CAS	379231-04-6
MW:	542.03 D

From 56.00€ *

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