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Ro 08-2750
Item number: Cay28772-1
Ro 08-2750 is a p75 neurotrophin receptor (p75NTR) ligand that completely inhibits nerve growth factor (NGF) binding to p75NTR in PC12 cells when used at a concentration of 100 µM. It also binds to NGF dimers (Kd = ~1 µM) to induce a conformational change that prevents NGF binding to p75NTR or tropomyosin-related...
| Keywords: | 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxo-benzo[g]pteridine-8-carboxaldehyde |
| Application: | p75 neurotrophin receptor (p75NTR) ligand |
| CAS | 37854-59-4 |
| MW: | 270.2 D |
From 58.00€
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Ro 08-2750
Item number: TGM-T16766-10mg
Description: Ro 08-2750 is a non-peptide, reversible nerve growth factor (NGF) inhibitor that binds to NGF with an IC50 of approximately 1 µM. It is also a selective MSI RNA-binding activity inhibitor, exhibiting an IC50 of 2.7 µM. Additionally, Ro 08-2750 selectively inhibits NGF binding to p75NTR over TRKA....
| Application: | p75 neurotrophin receptor (p75NTR) ligand |
| CAS | 37854-59-4 |
| MW: | 270.24 D |
From 58.00€
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