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SU 9516
Item number: Cay14796-1
SU 9516 is a 3-substituted indolinone that has anti-proliferative and pro-apoptotic activity in tumor cells. It is a potent inhibitor of several cyclin-dependent kinases (CDKs) with selectivity for Cdk2 (IC50s = 22, 40, and 200 nM for Cdk2/cyclin A, Cdk1/cyclin B, and Cdk4/cyclin D1). It does not inhibit PKC, p38,...
| Keywords: | 1,3-dihydro-3Z-(1H-imidazol-5-ylmethylene)-5-methoxy-2H-indol-2-one |
| Application: | Pro-apoptotic Cdk2/cyclin A inhibitor |
| CAS | 377090-84-1 |
| MW: | 241.3 D |
From 44.00€
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SU9516
Item number: TGM-T6167-100mg
Description: SU9516 is a potent CDK2 inhibitor with an IC50 of 22 nM and also inhibits CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively. Target: PKC, Apoptosis, CDK, p38 MAPK, Autophagy. Smiles: C(=C\1/C=2C(NC1=O)=CC=C(OC)C2)\C3=CN=CN3. References: Lane ME, et al. Cancer Res. 2001, 61(16), 6170-6177.
| Application: | CDK inhibitor |
| CAS | 377090-84-1 |
| MW: | 241.25 D |
From 31.00€
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SU-9516
Item number: LKT-S800000.100
CDK2 inhibitor.
| Keywords: | SU9516 |
| Application: | CDK inhibitor |
| CAS | 377090-84-1 |
| MW: | 241.25 D |
From 138.00€
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