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Item number: TGM-T3542-100mg

Description: BVT-14225, a selective 11beta-Hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitor, has an IC50 value of 52 nM. Target: Dehydrogenase. Smiles: CCN(CC)C(=O)Cc1csc(NS(=O)(=O)c2cccc(Cl)c2C)n1. References: Barf T, et al. Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs....

Keywords:	BVT 14225
Application:	11beta-HSD1 inhibitor
CAS	376638-65-2
MW:	401.93 D

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BVT 14225

Item number: Cay41224-1

BVT 14225 is an inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1, IC50s = 52 and 284 nM for the human and mouse enzymes, respectively). It is selective for human 11beta-HSD1 over human 11beta-HSD2 (IC50 = >10,000 nM). It inhibits 11beta-HSD1 by 55% in HEK293 cells expressing human HSD11B1, the...

Keywords:	2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-N,N-diethyl-4-thiazoleacetamide
Application:	11beta-HSD1 inhibitor
CAS	376638-65-2
MW:	401.9 D

From 35.00€ *

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