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Item number: Cay36534-100

Acebutolol is an antagonist of beta1-adrenergic receptors (beta1-ARs, Ki = 125 nM). It is selective for beta1- over beta2-ARs (Ki = 7,070 nM). In vivo, acebutolol decreases isoprenaline-induced tachycardia and diastolic hypotension in cats (ED50 = 0.09 mg/kg for both). Acebutolol (12.5, 25, and 50 mg/kg) inhibits...

Keywords:	M&B 17803A, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-butanamide
Application:	Beta1-AR antagonist
CAS	37517-30-9
MW:	336.4 D

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