Validamycin A is a fungicidal agent used to protect rice plants against sheath blight caused by the pathogenic fungus, R. solani, due to its ability to inhibit trehalase, a trehalose-hydrolizing enzyme (Ki = 1.9 nM, IC50 = 0.7 µM). It is also effective against the growth and sporulation of R. cerealis, F. culmorum,...

Description: Validamycin A is an antibiotic and fungicide that inhibits the alginate enzyme trehalase and thus protects crops from the fungus Rhizoctonia solani, as well as being a reversible inhibitor of tyrosinase. Target: Antifungal, Antibiotic, Tyrosinase. Smiles:...