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Item number: Cay14576-100

Diazoxide is an activator of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = 14.1 µM in a FLIPR assay using HEK293 cells). It also activates SUR2A/Kir6.2 and SUR2B/Kir6.2 channels in HEK293T cells in a patch-clamp assay when used at concentrations of 30 and 300 µM. Diazoxide...

Keywords:	NSC 64198, NSC 76130, SRG 95213, 7-chloro-3-methyl-1,1-dioxide-2H-1,2,4-benzothiadiazine
Application:	Potassium channel activator
CAS	364-98-7
MW:	230.7 D

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Diazoxide

Item number: TGM-T0126-100mg

Description: Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group. Target: ATPase, Autophagy, Potassium Channel. Smiles: O=S1(=O)C=2C(NC(C)=N1)=CC=C(Cl)C2. References:...

Keywords:	Proglycem, Sch-6783, SRG-95213
CAS	364-98-7
MW:	230.67 D

48.00€ *

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