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UBCS039
Item number: Cay43478-1
A SIRT6 activator, increases the deacetylation of an acetylated H3K9 peptide in a cell-free assay (EC50 = ~38 µM), selectively activates SIRT6 deacetylation activity over SIRT1, SIRT2, and SIRT3 deacetylation activities but does increase SIRT5 desuccinylation activity at 100 µM, active against M. tuberculosis (MIC =...
| Keywords: | 4,5-dihydro-4-(3-pyridinyl)-pyrrolo[1,2-a]quinoxaline |
| Application: | SIRT6 activator |
| CAS | 358721-70-7 |
| MW: | 247.3 D |
From 44.00€
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UBCS039
Item number: TGM-T7679-100mg
Description: UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 µM). Target: Autophagy, Sirtuin. Smiles: N1C(c2cccn2-c2ccccc12)c1cccnc1. References: Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.[J]. Cell death & disease, 2018.
| CAS | 358721-70-7 |
| MW: | 247.29 D |
From 33.00€
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