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2,8-Bis(trifluoromethyl)quinoline-4-carboxylic Acid

Item number: Cay43066-1

An agonist of PXR and active metabolite of mefloquine, increases the levels of CYP3A4 in a reporter assay using HepG2 cells expressing human PXR (EC50 = 24 µM), induces the expression of mRNA encoding MDR1, CYP2B6, and CYP3A4 in LS 174T cells

Keywords:	4-Carboxymefloquine, Mefloquine Carboxylic Acid, 2,8-bis(trifluoromethyl)-4-quinolinecarboxylic acid
Application:	PXR agonist, active mefloquine metabolite
CAS	35853-50-0
MW:	309.17 D

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