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Item number: Cay22292-1

N-desethyl Sunitinib is an active metabolite of sunitinib (Cay-13159), a small molecule, multi-targeted receptor tyrosine kinase inhibitor. N-desethyl Sunitinib is formed when sunitinib undergoes N-de-ethylation by the cytochrome P450 (CYP) isomer CYP3A4. N-desethyl Sunitinib is pharmacologically active having...

Keywords:	SU 12662, N-[2-(ethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-...
Application:	Active sunitinib metabolite, receptor tyrosine kinase inhibitor
CAS	356068-97-8
MW:	370.4 D

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N-Desethyl Sunitinib

Item number: TGM-T12145-1mL

Description: N-Desethyl Sunitinib (SU-11662) is a sunitinib metabolite. Target: c-Kit, VEGFR, PDGFR. Smiles: CCNCCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C. References: O'Farrell AM, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood. 2003 May...

Keywords:	SU-11662
CAS	356068-97-8
MW:	370.42 D

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