3-amino benzamide is an inhibitor of poly(ADP-ribose) polymerase (PARP, IC50 = 5.4 µM in C3H/10T1/2 mouse stem cells). It inhibits spontaneous, as well as FGF2-induced, invasiveness of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 50 µM. 3-amino benzamide (50 µM) induces...

White fluffy powder. A poly (ADP-ribose) Polymerase (PARP) inhibitor. PARP is a stress response protein activated by cytotoxic agents. It makes cells resistant to programmed cell death. Studies show that 3-aminobenzamide inhibits the modification of specific sites in a replicating DNA leading to inhibition of...