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NFAT Activation Inhibitor III
NFAT Activation Inhibitor III

Item number: Cay21812-10

NFAT activation inhibitor III is a cell-permeant inhibitor of signaling through nuclear factor of activated T cells (NFAT). It binds the substrate recognition site of the phosphatase calcineurin (Kd = 0.8 µM), preventing it from binding and dephosphorylating NFAT. NFAT activation inhibitor III blocks the nuclear...
Keywords: INCA-6, NSC 25996, 9,10-dihydro-9,10[1',2']-benzenoanthracene-1,4-dione
Application: Cell-permeant NFAT inhibitor
CAS 3519-82-2
MW: 284.3 D
From 93.00€ *
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INCA-6
INCA-6

Item number: TGM-T21807-100mg

Description: INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor that disrupts CN-NFAT signaling by targeting the NFAT(P) substrate at the calcineurin (CN) phosphatase site. Target: Others. Smiles: O=C1C=CC(=O)C2=C1C1c3ccccc3C2c2ccccc12. References: Colin A Bretz, et al. The role of the NFAT signaling...
Keywords: Triptycene-1,4-quinone
CAS 3519-82-2
MW: 284.31 D
From 30.00€ *
Review