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GNTI (hydrochloride)
Item number: Cay31597-1
GNTI is a kappa-opioid receptor antagonist (Ki = 0.18 nM). It is selective for kappa-opioid receptors over µ- and delta-opioid receptors in radioligand binding assays (Kis = 36.9 and 70 nM, respectively). GNTI inhibits agonist-induced [35S]GTPgammaS binding in CHO cells expressing human kappa-opioid receptors (pA2 =...
| Keywords: | 5'-Guanidinonaltrindole,... |
| Application: | kappa-opioid receptor antagonist |
| CAS | 351183-88-5 |
| MW: | 544.5 D |
From 85.00€
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GNTI dihydrochloride
Item number: TGM-T22802-10mg
Description: kappa opioid receptor antagonist. Target: Others. Smiles: Cl.Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1c2[nH]c2ccc(NC(N)=N)cc12)ccc3O. References: Zheng X, Bauer P, Baumeister T, et al. Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (Nampt)...
| CAS | 351183-88-5 |
| MW: | 508.01 D |
From 187.00€
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