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Item number: Cay15029-25

UK 383367 is a potent inhibitor of bone morphogenetic protein 1 (BMP1, IC50 = 44 nM). It is more than 200-fold selective for BMP1 over a panel of matrix metalloproteinases. UK 383367 is effective in a cell-based model of collagen deposition is very effective at penetrating human skin in vitro.Formal Name:...

Keywords:	(betaR)-3-(aminocarbonyl)-beta-(3-cyclohexylpropyl)-N-hydroxy-1,2,4-oxadiazole-5-propanamide
Application:	BMP-1 inhibitor
CAS	348622-88-8
MW:	324.4 D

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UK-383367

Item number: TGM-T6064-10mg

Description: UK-383367 is a procollagen C-proteinase inhibitor with IC50 of 44 nM, has excellent selectivity over MMPs. Target: Procollagen C Proteinase. Smiles: NC(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO. References: Fish PV, et al. J Med Chem, 2007, 50(15), 3442-3456.

Keywords:	UK 383367
Application:	BMP-1 inhibitor
CAS	348622-88-8
MW:	324.38 D

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