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Item number: TGM-T3638-100mg

Description: Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration, reduces inflammation. Target: Integrin, Complement System. Smiles: OC(=O)c1ccc(cc1)-c1ccc(\C=C2/SC(=S)N(Cc3ccccc3)C2=O)o1....

Application:	Allosteric CD11b/CD18 activator
CAS	344897-95-6
MW:	421.49 D

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Leukadherin 1

Item number: Cay14855-10

Leukadherin 1 is a small molecule allosteric activator of CD11b/CD18 that increases K562 cell adhesion to an endogenous CD11b/CD18 ligand, fibrinogen (EC50 = 4 µM). It increases adhesion and decreases de-adhesion of murine neutrophils, leading to reduced chemotaxis. It acts by reducing the rolling velocity of...

Keywords:	4-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid
Application:	Allosteric CD11b/CD18 activator
CAS	344897-95-6
MW:	421.5 D

From 83.00€ *

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