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Item number: Cay19170-1

CP-673,451 is a selective inhibitor of the platelet-derived growth factor receptor beta (PDGFRbeta) kinase with an IC50 value of 1 nM. It also inhibits the PDGFRalpha kinase (IC50 = 10 nM), but exhibits greater than 450-fold selectivity over other angiogenic receptors such as VEGFR 2, TIE-2, and FGR2. In several in...

Keywords:	1-[2-[5-(2-methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine
Application:	PDGFRbeta inhibitor
CAS	343787-29-1
MW:	417.5 D

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