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CAY10404
Item number: Cay70210-1
CAY10404 is an inhibitor of COX-2 (IC50 = 50 = >500 µM). CAY10404 inhibits the proliferation of SH-EP and SH-SY5Y neuroblastoma cells (IC50s = ~60 µM for both), and induces apoptosis and cell cycle arrest at the G2/M phase in the same cells. It inhibits carrageenan-induced paw edema in rats when administered at a...
| Keywords: | 3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole |
| Application: | COX-2 inhibitor |
| CAS | 340267-36-9 |
| MW: | 367.4 D |
From 37.00€
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CAY10404
Item number: TGM-T8656-100mg
Description: CAY10404 (3-(4-METHYLSULPHONYLPHE NYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cells, with analgesic, anti-inflammatory and anti-cancer activities. Target: Akt,...
| Keywords: | 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T |
| Application: | COX-2 inhibitor |
| CAS | 340267-36-9 |
| MW: | 367.34 D |
From 33.00€
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