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Item number: Cay70210-1

CAY10404 is an inhibitor of COX-2 (IC50 = 50 = >500 µM). CAY10404 inhibits the proliferation of SH-EP and SH-SY5Y neuroblastoma cells (IC50s = ~60 µM for both), and induces apoptosis and cell cycle arrest at the G2/M phase in the same cells. It inhibits carrageenan-induced paw edema in rats when administered at a...

Keywords:	3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole
Application:	COX-2 inhibitor
CAS	340267-36-9
MW:	367.4 D

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