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Item number: Cay75780-10

20-HETE is a major biologically active cytochrome P450 (CYP450) metabolite of arachidonic acid in the kidney and liver. It regulates renal vascular and tubular functions as well as vascular tone in the cerebral circulation. HET0016 is an inhibitor of 20-HETE formation in human renal microsomes with an IC50 of 8.9...

Keywords:	N-hydroxy-N'-(4-n-butyl-2-methylphenyl)Formamidine, N-(4-butyl-2-methylphenyl)-N'-hydroxy-methanimidamide
Application:	Bioactive lipid assays
CAS	339068-25-6
MW:	206.3 D

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HET0016

Item number: TGM-T11556-1mg

Description: HET0016 is a potent and selective 20-HETE synthase inhibitor (IC50s: 17.7 nM, 12.1 nM, and 20.6 nM for recombinant CYP4A1-, CYP4A2-, and CYP4A3-catalyzed 20-HETE synthesis) and a selective CYP450 inhibitor, shown to inhibit angiogenesis and tumor growth. Target: Others. Smiles: CCCCc1ccc(N=CNO)c(C)c1....

CAS	339068-25-6
MW:	206.28 D

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