Description: Silychristin (Silicristin) is a plant growth regulator. Silychristin is an anti-hepatotoxic agent. Silychristin is the inhibitor of horseradish peroxidases and lipoxygenase. Target: Lipoxygenase. Smiles: COc1cc(ccc1O)[C@@H]1Oc2c(cc(cc2O)[C@H]2Oc3cc(O)cc(O)c3C(=O)[C@@H]2O)[C@H]1CO. References: Vavríková...

Silychristin is a flavonolignan that has been found in S. marianum and has diverse biological activities. It inhibits monocarboxylate transporter 8 (MCT8, IC50 = ~100 nM) and MCT8-dependent uptake of the thyroid hormone 3,3',5-triiodo-L-thyronine (T3) in MDCK cells and primary mouse astrocytes (IC50s = 170 and 50...