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Item number: Cay45333-1

An inhibitor of KCa2.1/SK1 and KCa2.2/SK2 (IC50 = 43 and 123 nM, respectively, in HEK293 cells expressing the rat channels), prolongs atrial action potential duration and AERP and reduces burst pacing-induced atrial fibrillation in isoprenaline- or carbachol-stimulated isolated rat atrial tissue at 10 µM, active...

Keywords:	N-[4-(2-pyridinyl)-2-thiazolyl]-2-pyridinamine
Application:	KCa2.1/SK1 / KCa2.2/SK2 inhibitor
CAS	3374-88-7
MW:	254.31 D

From 97.00€ *

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ICA

Item number: TGM-T15546-100mg

Description: ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM). Target: Parasite, Potassium Channel. Smiles: N(c1nc(cs1)-c1ccccn1)c1ccccn1. References: Bhuniya D, et al. Aminothiazoles: Hit to lead development to identify...

Keywords:	N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine
CAS	3374-88-7
MW:	254.31 D

From 58.00€ *

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