White solid. Soluble in DMSO, methanol, acetone or dichloromethane. Insoluble in hexane or water. 20-Membered macrolide glycoside, Antibiotic and antifungal agent, Shows antitrypanosomal and antimalarial activity, Potent inhibitor of mitochondrial and bacterial ATP synthase, Inhibitor of F0F1-ATPase,...

Venturicidin A is a macrolide antibiotic isolated from strains of Streptomyces. It is active against fungi in the genus Venturia which cause apple scab, as well as other fungi, but not against higher plants. Venturicidin A is also cytotoxic against trypanosomes (IC50 = 120-540 ng/ml) while being more than 25,000...

The macrolide antibiotic Venturicidin A, isolated from a Streptomyces sp., is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. Originally isolated as an antifungal agent. Storage and Stability: Lyophilized powder may be stored at 4°C. Stable for 12 months at 4°C. For maximum...

Description: Venturicidin A is a macrolide antibiotic. Target: Others. Smiles: [H][C@@]1(C[C@@H](OC(N)=O)[C@H](O)[C@@H](C)O1)O[C@@H]1CCC\C=C(C)\[C@@]2([H])O[C@](O)(CC=C2C)CC(=O)O[C@]([H])([C@H](C)C[C@@H](C)[C@H](O)[C@H](C)C(=O)CC)[C@H](C)C[C@@H](C)\C=C\1