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Item number: TGM-T5210-100mg

Description: BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 µM). Target: BCL, Apoptosis. Smiles: OC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12. References: Bombrun A, et al. 3,6-dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of...

Application:	Bax inhibitor
CAS	335165-68-9
MW:	467.2 D

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Bax Channel Blocker

Item number: Cay37538-10

Bax channel blocker is an inhibitor of Bax. It binds to Bax in a cell-free assay (Kd = 15 µM) and inhibits Bax-mediated membrane permeabilization induced by the membrane-targeted death ligand tBID in a liposomal release assay (IC50 = 3.3 µM). Bax channel blocker inhibits apoptosis induced by TNF-alpha- and the...

Keywords:	BAI1, 3,6-dibromo-alpha-(1-piperazinylmethyl)-9H-carbazole-9-ethanol
Application:	Bax inhibitor
CAS	335165-68-9
MW:	467.2 D

From 45.00€ *

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