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Item number: Cay43190-1

MEK inhibitor is an inhibitor of MEK5 (IC50 = 1. nM). It is selective for MEK5 over ERK5, activin receptor-like kinase 5 (ALK5), also known as TGF-beta receptor type I (TGF-betaRI), MEK1, and MEK2 (IC50s = 59, 580, >6,300, and >6,300 nM, respectively) and a panel of 79 other kinases at 10 µM. MEK inhibitor (1, 3, or...

Keywords:	BIX02189, (3Z)-3-[[[3-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-N-methyl-2-oxo-1H-indole-6-carboxamide
Application:	MEK5 (MAP2K5) inhibitor
CAS	334951-92-7
MW:	426.52 D

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