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Item number: Cay21897-1

VU0071063 is a potent and selective activator of the inward-rectifier potassium channel (Kir) 6.2 and sulfonylurea receptor (SUR) 1 (EC50 = 7 µM using whole cell patch clamp electrophysiology). It is selective for SUR1-containing Kir6.1 or Kir6.2 channels over SUR2A, Kir2.1, Kir2.2, Kir2.3, Kir3.1/3/2, and...

Keywords:	7-[[4-(1,1-dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
Application:	Kir6.2 / SUR activator
CAS	333415-38-6
MW:	326.4 D

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VU0071063

Item number: TGM-T26324-100mg

Description: VU0071063 is a Kir6.2/SUR1 activator. Target: Potassium Channel. Smiles: Cn1c2ncn(Cc3ccc(cc3)C(C)(C)C)c2c(=O)n(C)c1=O. References: Raphemot R, Swale DR, Dadi PK, Jacobson DA, Cooper P, Wojtovich AP, Banerjee S, Nichols CG, Denton JS. Direct activation of beta-cell KATP channels with a novel xanthine...

Keywords:	VU 0071063, VU-0071063
CAS	333415-38-6
MW:	326.39 D

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