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1,4-DPCA
Item number: TGM-T21653-100mg
Description: 1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 µM for factor inhibiting HIF (FIH). Target: HIF/HIF Prolyl-Hydroxylase. Smiles: OC(=O)C1=CN=C2C(C=Cc3cccnc23)C1=O. References: Gaofeng Xiong, et al. Prolyl-4-hydroxylase...
| CAS | 331830-20-7 |
| MW: | 240.21 D |
From 46.00€
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1,4-DPCA
Item number: Cay71220-10
The pro-angiogenic factor HIF-1alpha is targeted for destruction in non-hypoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). Inhibitors of prolyl 4-hydroxylase are potentially useful in controlling excess collagen...
| Keywords: | 1,4-dihydrophenonthrolin-4-one-3-Carboxylic acid, 4,4alpha-dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid |
| Application: | Prolyl 4-hydroxylase inhibitor |
| CAS | 331830-20-7 |
| MW: | 240.2 D |
From 67.00€
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1,4-DPCA
Item number: LKT-D6108.25
Prolyl hydroxylase inhibitor.
| Keywords: | 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid, 3-Acetyl-1H-[1,10]phenanthrolin-4-one,... |
| Application: | Prolyl hydroxylase inhibitor |
| CAS | 331830-20-7 |
| MW: | 240.22 D |
From 76.00€
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