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Item number: TGM-T3635-100mg

Description: IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions, and so on. Target: Wnt/beta-catenin. Smiles: CC(=O)c1ccc(cc1)\N=N\C(\C(N)=O)=C1\NC(C)(C)Cc2ccccc12. References: Sasaki T, et al. PLoS One. 2013,...

Keywords:	IQ-1, IQ1
Application:	Cell-permeable embryonic stem cell (ESC) pluripotency keeper
CAS	331001-62-8
MW:	362.42 D

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IQ-1

Item number: Cay16153-5

IQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that maintains long-term mouse embryonic stem cell (ESC) pluripotency. When used at 4 µg/ml with Wnt3a, it allows ESCs to form embryoid bodies that continue to express markers of pluripotency, including alpha-fetoprotein and beta-III tubulin. IQ-1 blocks...

Keywords:	2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
Application:	Cell-permeable embryonic stem cell (ESC) pluripotency keeper
CAS	331001-62-8
MW:	362.4 D

From 145.00€ *

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