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Item number: Cay14930-10

Vardenafil is a potent inhibitor of phosphodiesterase 5 (PDE5, IC50s = 0.2-1.2 nM) and PDE6 (IC50 = 2 nM). It is selective for PDE5 and PDE6 over PDE1 and PDE11 (IC50s = 230 and 130 nM, respectively). Vardenafil (4 mg/kg per day for three weeks) improves erectile function in a rat model of acute arteriogenic...

Keywords:	2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one,...
Application:	PDE5 inhibitor
CAS	330808-88-3
MW:	579.1 D

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