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Monastrol
Item number: TGM-T4048-100mg
Description: Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5. Target: Kinesin, Apoptosis. Smiles: CCOC(=O)C1=C(C)NC(=S)NC1c1cccc(O)c1. References: Cochran JC, et al. Monastrol inhibition of the mitotic kinesin Eg5. J BiolChem. 2005 Apr 1,280(13):12658-67.
| Keywords: | (±)-Monastrol |
| Application: | Kinesin-like protein KIF11 / Eg5 inhibitor |
| CAS | 329689-23-8 |
| MW: | 292.35 D |
From 42.00€
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Monastrol
Item number: Cay15044-5
Monastrol is a reversible, cell-permeable inhibitor of the motor protein Eg5 (kinesin family protein 11, Kif11), blocking basal ATPase activity in vitro (IC50 = 6.1 µM) and inducing the formation of monoastral spindles in cell-based assays (IC50 = 51.3 µM). It arrests cells in mitosis without targeting tubulin and,...
| Keywords: | 1,2,3,4-tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-thioxo-5-pyrimidinecarboxylic acid, ethyl ester |
| Application: | Kinesin-like protein KIF11 / Eg5 inhibitor |
| CAS | 329689-23-8 |
| MW: | 292.4 D |
From 94.00€
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