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SANT-2
Item number: Cay21208-5
SANT-2 is a Smoothened (Smo) receptor antagonist. It binds to the Smo receptor (Kd = 12 nM) and inhibits binding of the Smo receptor agonist SAG-1.3 (SAG, Cay-11914) and antagonist cyclopamine (Cay-11321) (Kis = 7.8 and 8.4 nM, respectively). SANT-2 inhibits hedgehog signaling induced by an N-terminal fragment of...
| Keywords: | N-[3-(1H-benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxy-benzamide |
| Application: | Hh signaling Antagonist |
| CAS | 329196-48-7 |
| MW: | 480 D |
From 110.00€
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SANT-2
Item number: AG-CR1-3514-M001
Cell permeable potent smoothened (Smo) antagonist. Inhibits wt and oncogenic Smo. Tool to study hedgehog (Hh) signaling pathway. SAG activity (Prod. Nr. AG-CR1-3506) inhibitor. Gli1 reporter gene expression inhibitor. Suppresses the Shh-dependent translocation of Smo to the primary cilium. Potential tumor growth...
| Keywords: | N-[3-(1H-Benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide |
| Application: | Smo antagonist |
| CAS | 329196-48-7 |
| MW: | 480 D |
From 44.00€
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SANT 2
Item number: TGM-T23307-2mg
Description: SANT 2 is a Hedgehog (Hh) signaling pathway antagonist with potential anti-inflammatory and anticancer activity for the study of prostate, pancreatic and breast cancer. Target: Hedgehog/Smoothened. Smiles: O=C(NC=1C=CC(Cl)=C(C1)C2=NC=3C=CC=CC3N2)C4=CC(OCC)=C(OCC)C(OCC)=C4
| Keywords: | SANT-2 |
| Application: | Smo antagonist |
| CAS | 329196-48-7 |
| MW: | 479.96 D |
From 29.00€
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