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6-Aminonicotinamide
Item number: Cay10009315-100
6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase (Ki = 0.46 µM). Through this action, 6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells...
| Keywords: | 6-AN, NSC 21206, SR 4388, 6-amino-3-pyridinecarboxamide |
| Application: | 6-phosphogluconate dehydrogenase inhibitor |
| CAS | 329-89-5 |
| MW: | 137.1 D |
From 20.00€
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6-Aminonicotinamide
Item number: LKT-A4940.250
Very faint yellow crystalline powder. It induces apoptosis in tumor cells. Member of the drug combination called PMA which induces regression of murine mammary tumors by depleting ATP.
| Keywords: | e-Aminocaproic Acid, EACA, Amicar, Capracid, Epsikapron, Hemocaprol, Ipsilon |
| Application: | Apoptosis inducer |
| CAS | 329-89-5 |
| MW: | 137.14 D |
From 90.00€
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