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Item number: Cay15772-10

The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 µM). This compound binds to a site at the external pore of...

Keywords:	Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor II, GlyH-101,...
Application:	CF transmembrane conductance regulator inhibitor
CAS	328541-79-3
MW:	493.2 D

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GlyH-101

Item number: TGM-T2451-100mg

Description: GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM. Target: Autophagy, CFTR. Smiles: OC1=C(Br)C(=O)\C(=C\NNC(=O)CNc2ccc3ccccc3c2)C=C1Br. References: Muanprasat C, et al. J Gen Physiol. 2004, 124(2), 125-137.

Keywords:	GlyH 101
CAS	328541-79-3
MW:	493.15 D

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