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Item number: Cay15342-5

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. Phortress is a lysyl amide prodrug of the benzothiazole 5-fluoro 203...

Keywords:	NSC 710305, 2S,6-diamino-N-[4-(5-fluoro-2-benzothiazolyl)-2-methylphenyl]-hexanamide, dihydrochloride
Application:	AhR ligand prodrug
CAS	328087-38-3
MW:	459.4 D

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Phortress

Item number: TGM-T23151-100mg

Description: Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor activity. Target: AhR. Smiles: CC1=C(NC([C@@H](N)CCCCN)=O)C=CC(C2=NC3=CC(F)=CC=C3S2)=C1.Cl.Cl. References: Bradshaw TD, et al. In vitro evaluation of...

Keywords:	NSC 710305
CAS	328087-38-3
MW:	459.41 D

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