4 products were found matching "327036-89-5"!
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TDZD-8
Item number: LKT-T1298.5
An inhibitor of glycogen synthase kinase-3 (GSK3) beta, which was found to be a key intermediate in apoptotic signaling associated with neurodegenerative diseases such as Parkinson. Protect from light. Packaged under inert gas.
| Keywords: | 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione |
| Application: | GSK3 beta inhibitor |
| CAS | 327036-89-5 |
| MW: | 222,26 D |
From 128.00€
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TDZD-8
Item number: Cay16287-25
TDZD-8 is a thiadiazolidine derivative that acts as a non-ATP competitive inhibitor of the serine/threonine kinase glycogen synthase kinase 3beta (GSK3beta, IC50 = 2 µM), binding to the active site of GSK3beta. It does not significantly affect the activities of Cdk-1/cyclin B, CK-II, cAMP-dependent protein kinase,...
| Keywords: | GSK3beta Inhibitor I, NP 01139, 2-methyl-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione |
| Application: | GSK3-beta inhibitor |
| CAS | 327036-89-5 |
| MW: | 222.3 D |
From 95.00€
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TDZD-8
Item number: AG-CR1-3740-M005
White to off-white powder. Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (20mg/ml). Chemical. CAS: 327036-89-5. Formula: C10H10N2O2S. MW: 222.3. TDZD-8 is a non-ATP competitive selective inhibitor of the serine/threonine kinase glycogen synthase kinase 3beta (GSK3beta, IC50 = 2µM), binding to the active site...
| Keywords: | NP 01139, 2-Methyl-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione |
| Application: | Non-ATP competitive selective GSK3beta inhibitor |
| CAS | 327036-89-5 |
| MW: | 222,3 D |
From 55.00€
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TDZD-8
Item number: TGM-T6187-100mg
Description: TDZD-8 (NP 01139) is an inhibitor of GSK-3beta, with an IC50 of 2 µM, minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC. Target: GSK-3. Smiles: Cn1sc(=O)n(Cc2ccccc2)c1=O. References: Martinez A, et al. J Med Chem, 2002, 45(6), 1292-1299.
| Keywords: | NP 01139, GSK-3beta Inhibitor I |
| Application: | Non-ATP competitive selective GSK3beta inhibitor |
| CAS | 327036-89-5 |
| MW: | 222.26 D |
From 40.00€
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