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Item number: Cay45148-1

A multi-kinase inhibitor and derivative of sunitinib, inhibits VEGFR1, VEGFR2, PDGFR, and c-Kit (IC50s = 0.013, 0.017, 0.005, and 0.04 µM, respectively), reduces the degradation of cartilage proteoglycan and the severity of arthritis in the K/BxN mouse model of rheumatoid arthritis at 40 mg/kg, reduces intratumoral...

Keywords:	SU 11657,...
Application:	Sunitinib derivative, multi-kinase inhibitor
CAS	326914-17-4
MW:	370.43 D

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