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Item number: Cay18674-10

Diphenidol is an antagonist of muscarinic acetylcholine receptors (mAChRs, Kis = 0.43, 2.8, 1.1, 0.91, and 1.28 µM in CHO cell membranes expressing M1-5 receptors, respectively). It also inhibits Kv channels in Neuro2A cells (IC50 = 28.2 µM), as well as L-type voltage-gated calcium channels in differentiated NG...

Keywords:	SKF 478A, alpha,alpha-diphenyl-1-piperidinebutanol, monohydrochloride
Application:	Muscarinic acetylcholine receptor antagonist, antiemetic
CAS	3254-89-5
MW:	345.9 D

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Diphenidol hydrochloride

Item number: TGM-T0862-100mg

Description: Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug. Target: AChR, Sodium Channel. Smiles: Cl.OC(CCCN1CCCCC1)(c1ccccc1)c1ccccc1. References: Leung YM, et al. Pharmacol Rep. 2012,64(3):739-44.

Keywords:	Difenidol hydrochloride, Diphenidol HCl
CAS	3254-89-5
MW:	345.91 D

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