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Cytosporone B
Cytosporone B

Item number: Cay17501-1

Cytosporone B is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene for Nur77 itself. Signaling through Nur77 induces apoptosis in cancer cells and retards xenograft tumor growth....
Keywords: Csn-B, Dothiorelone G, 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetic acid, ethyl ester
Application: Nur77 agonist
CAS 321661-62-5
MW: 322.4 D
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