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Item number: Cay16277-1

Polycomb complex protein BMI-1 is a polycomb ring finger oncogene that regulates the p16 and p19 cell cycle inhibitor genes. It is necessary for efficient self-renewing cell divisions of stem cells in several tissues and can be over-expressed in tumors. PTC-209 is a BMI-1 inhibitor (IC50 = ~ 0.5 µM) that...

Keywords:	N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-2-thiazolamine
Application:	BMI-1 inhibitor
CAS	315704-66-6
MW:	495.2 D

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PTC-209

Item number: TGM-T2345-100mg

Description: PTC-209 is a potent and selective BMI-1 inhibitor. Target: Autophagy, BMI-1. Smiles: COc1cc(Br)c(Nc2nc(cs2)-c2c(C)nc3ncccn23)c(Br)c1. References: Kreso A, et al. Nat Med. 2014, 20(1), 29-36.

Keywords:	PTC 209, PTC209
CAS	315704-66-6
MW:	495.19 D

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