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ML311
Item number: TGM-T5108-100mg
Description: ML311 is a selective inhibitor of the Mcl-1/Bim interaction. Target: BCL. Smiles: CCN1CCN(CC1)C(c1ccc(cc1)C(F)(F)F)c1ccc2cccnc2c1O. References: Bannister T, et al. ML311: A Small Molecule that Potently and Selectively Disrupts the Protein-Protein Interaction of Mcl-1 and Bim: A Probe for Studying...
| Application: | Mcl-1 inhibitor |
| CAS | 315698-17-0 |
| MW: | 415.45 D |
From 37.00€
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ML-311
Item number: Cay29445-1
ML-311 is an inhibitor of myeloid cell leukemia-1 (Mcl-1, IC50 = 0.31 µM in a fluorescence polarization assay). It is selective for Mcl-1 over Bcl-xL (IC50 = >40 µM). ML-311 decreases the proliferation of 13 cancer cell lines (EC50s = 0.3-25 µM).Formal Name:...
| Keywords: | 7-[(4-ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol |
| Application: | Mcl-1 inhibitor |
| CAS | 315698-17-0 |
| MW: | 415.5 D |
From 52.00€
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