TC-DAPK6 is an inhibitor of death-associated protein kinase 1 (DAPK1) and DAPK3 (IC50s = 69 and 225 nM, respectively). It is selective for DAPK1 and DAPK3 over 47 other kinases at 10 µM. Hollow mesoporous silica nanocarriers (HMSNs) encapsulating TC-DAPK6 increase the latency to fall and distance traveled on the rod...

Description: TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3. Target: DAPK. Smiles: C(=C1C(=O)OC(C=CC2=CC=CC=C2)=N1)C=3C=CC=NC3. References: Okamoto M, et al. Identification of death-associated protein kinases inhibitors using...