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Item number: Cay43167-10

INT-131 is a partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It binds to PPARgamma (IC50 = 0. µM) and induces PPARgamma transactivation in HEK293 cells expressing the human receptor (EC50 = 0. µM). INT-131 (30 mg/kg) reduces blood glucose and insulin levels in KKAy diabetic mice. It...

Keywords:	AMG 131, 2,4-dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]-benzenesulfonamide
Application:	Partial PPAR gamma agonist
CAS	315224-26-1
MW:	514.2 D

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AMG131

Item number: TGM-T8780-1mg

Description: AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin dependent diabetes). Target: PPAR. Smiles:...

Keywords:	INT-131, AMG-131, CHS 131
CAS	315224-26-1
MW:	514.21 D

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